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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC14
All Species:
33.03
Human Site:
S291
Identified Species:
60.56
UniProt:
Q8IZN3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZN3
NP_078906.2
488
53388
S291
E
D
I
K
G
S
W
S
N
K
R
G
K
E
N
Chimpanzee
Pan troglodytes
XP_001143896
464
50937
S267
E
D
I
K
G
S
W
S
N
K
R
G
K
E
N
Rhesus Macaque
Macaca mulatta
XP_001093039
488
53343
S291
E
D
I
K
G
S
W
S
N
K
R
G
K
E
N
Dog
Lupus familis
XP_854971
420
45636
G227
G
S
W
S
N
K
R
G
K
E
N
Y
N
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQQ1
489
53640
S291
E
D
I
K
G
S
W
S
N
K
R
G
K
E
N
Rat
Rattus norvegicus
Q2TGJ1
386
41641
C192
Q
M
V
K
L
K
Y
C
F
T
C
K
M
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232232
491
53709
S293
E
D
I
K
G
S
W
S
N
K
R
G
K
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038652
513
56361
S310
E
D
I
K
G
S
W
S
S
K
R
G
K
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137936
693
74989
S274
E
D
L
K
G
S
F
S
S
K
G
G
P
R
T
Honey Bee
Apis mellifera
XP_395517
664
74472
S259
E
D
I
K
G
S
F
S
I
K
T
G
Q
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796142
543
59493
S322
E
D
I
K
G
A
W
S
K
K
H
D
Q
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SB58
407
46728
V214
M
D
H
Q
Q
A
T
V
W
R
A
M
K
E
S
Baker's Yeast
Sacchar. cerevisiae
Q06551
359
41080
I166
T
L
P
T
H
S
S
I
S
K
D
I
T
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.8
80.9
N.A.
94.8
50.4
N.A.
N.A.
89.6
N.A.
66.6
N.A.
37.2
41.8
N.A.
41.9
Protein Similarity:
100
95
100
82.7
N.A.
97.7
58.6
N.A.
N.A.
93.8
N.A.
76.2
N.A.
50.2
51.6
N.A.
57
P-Site Identity:
100
100
100
0
N.A.
100
6.6
N.A.
N.A.
100
N.A.
86.6
N.A.
53.3
73.3
N.A.
53.3
P-Site Similarity:
100
100
100
6.6
N.A.
100
26.6
N.A.
N.A.
100
N.A.
93.3
N.A.
73.3
86.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.7
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
0
77
0
0
0
0
0
0
0
0
8
8
0
8
0
% D
% Glu:
70
0
0
0
0
0
0
0
0
8
0
0
0
54
0
% E
% Phe:
0
0
0
0
0
0
16
0
8
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
70
0
0
8
0
0
8
62
0
8
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
62
0
0
0
0
8
8
0
0
8
0
8
0
% I
% Lys:
0
0
0
77
0
16
0
0
16
77
0
8
54
0
8
% K
% Leu:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
39
0
8
0
8
0
54
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% P
% Gln:
8
0
0
8
8
0
0
0
0
0
0
0
16
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
47
0
0
8
8
% R
% Ser:
0
8
0
8
0
70
8
70
24
0
0
0
0
0
8
% S
% Thr:
8
0
0
8
0
0
8
0
0
8
8
0
8
0
8
% T
% Val:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
54
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _